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In previous Phase 2 clinical trials, participants reported an average weight loss of about 22.8% (with an 8mg dose) and 24.2% (with 12mg) after retatrutide for 11 months
The abrupt cessation of GLP-1R agonists in individuals with metabolic disorders may lead to adverse effects, as seen in a case where a patient developed IIH after discontinuing duraglutide [29]
But I think the next point that you're making is that the label, what the PBM is saying is you can't do utilization management that deviates from the label
The National Institute for Health and Care Excellence (NICE) in the UK recommends CCB as first-line in those over 55 years or patients of any age from Black African or African-Caribbean family origin
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